Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894134 | 0.94 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL23080295 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL9516460 | 0.85 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL27334398 | 0.84 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL13638135 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL10587847 | 0.82 | ALDH1A1 (0.83) | SMN1; SMN2ALDH1A1HPGDNPSR1EPHX1 | |
| SCHEMBL19308752 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL19308746 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL13638136 | 0.81 | LMNA (0.60) | SMN1; SMN2ALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL11804456 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HPGDNPSR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60004163-A | — | — | None | — | — | JP | disclosed |
| JP-S604163-A | SULFIDE COMPOUND | TAIHO YAKUHIN KOGYO KK | 1985-01-10 | — | — | JP | disclosed |