Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308752 | 1.00 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDTSHRNPSR1 | |
| SCHEMBL9516460 | 0.91 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2HPGDTSHRNPSR1 | |
| SCHEMBL13638136 | 0.87 | LMNA (0.60) | ALDH1A1SMN1; SMN2HPGDTSHRNPSR1 | |
| SCHEMBL10982270 | 0.81 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2HPGDTSHRNPSR1 | |
| SCHEMBL11804456 | 0.78 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2HPGDNPSR1HDAC3 | |
| SCHEMBL931479 | 0.78 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2HPGDNPSR1HDAC3 | |
| SCHEMBL13638135 | 0.78 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2HPGDTSHRNPSR1 | |
| SCHEMBL10587847 | 0.78 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2HPGDNPSR1HDAC3 | |
| SCHEMBL2752779 | 0.76 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2HPGDNPSR1HDAC3 | |
| SCHEMBL25619252 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752153-B2 | Alkynyl-derivatized cap analogs, preparation and uses thereof | Life Technologies Corporation (US) | 2017-09-05 | — | — | US | disclosed |