Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638136 | 0.91 | LMNA (0.60) | ALDH1A1SMN1; SMN2HPGDTSHREPHX1 | |
| SCHEMBL19308752 | 0.91 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDTSHREPHX1 | |
| SCHEMBL19308746 | 0.91 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HPGDTSHREPHX1 | |
| SCHEMBL10587847 | 0.85 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2HPGDEPHX1KMT2A | |
| SCHEMBL10982270 | 0.85 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2HPGDTSHREPHX1 | |
| SCHEMBL13638135 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2HPGDTSHREPHX1 | |
| SCHEMBL23419601 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HPGDEPHX1KMT2A | |
| SCHEMBL20650992 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HPGDEPHX1KMT2A | |
| SCHEMBL22061771 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HPGDEPHX1KMT2A | |
| SCHEMBL10078357 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HPGDEPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5118681-A | Bactericides | ROHM AND HAAS COMPANY (US) | 1992-06-02 | — | — | US | disclosed |