Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361342 | 0.82 | CTRC (0.33) | — | |
| SCHEMBL1515036 | 0.79 | CTRC (0.30) | — | |
| SCHEMBL1098786 | 0.79 | TDP1 (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL21930004 | 0.77 | TDP1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL5742793 | 0.76 | — | — | |
| SCHEMBL3370665 | 0.74 | — | — | |
| SCHEMBL17372500 | 0.74 | ALOX5 (0.32) | — | |
| SCHEMBL19554636 | 0.74 | — | — | |
| SCHEMBL8409370 | 0.71 | — | — | |
| SCHEMBL3477755 | 0.70 | EPHX2 (0.46) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765844-B1 | PURINE NUCLEOTIDE DERIVATIVES | SOLVELL AS (NO) | 2014-07-30 | — | — | EP | disclosed |
| US-8153609-B2 | Purine nucleotide derivatives | LAURAS AS (NO) | 2012-04-10 | — | — | US | disclosed |
| US-20080293665-A1 | Purine Nucleotide Derivatives | LAURAS AS (NO) | 2008-11-27 | — | — | US | disclosed |
| EP-1765844-A2 | PURINE NUCLEOTIDE DERIVATIVES | Lauras AS (NO) | 2007-03-28 | — | — | EP | disclosed |
| US-7163946-B2 | 5-substituted 7,9-difluoro-5H-chromeno[3,4-f]quinoline compounds as selective progesterone receptor modulator compounds | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-01-16 | — | — | US | disclosed |
| WO-2005123755-A2 | PURINE NUCLEOTIDE DERIVATIVES | LAURAS AS (NO) | 2005-12-29 | — | — | WO | disclosed |
| EP-1554283-A1 | 5-SUBSTITUTED 7,9-DIFLUORO-5 I H /I -CHROMENO (3,4-F) QUINOLINE COMPOUNDS AS SELECTIVE PROGESTERONE RECEPTOR MODULATORS | LIGAND PHARMACEUTICALS, INC. (US) | 2005-07-20 | — | — | EP | disclosed |
| US-20040152717-A1 | 5-Substituted 7,9-difluoro-5H-chromeno[3,4-f]quinoline compounds as selective progesterone receptor modulator compounds | LIGAND PHARMACEUTICALS INC. | 2004-08-05 | — | — | US | disclosed |
| WO-2004033461-A1 | 5-SUBSTITUTED 7,9-DIFLUORO-5H-CHROMENO[3,4-f]QUINOLINE COMPOUNDS AS SELECTIVE PROGESTERONE RECEPTOR MODULATORS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152717-A1 | 5-Substituted 7,9-difluoro-5H-chromeno[3,4-f]quinoline compounds as selective progesterone receptor modulator compounds | PGR, FSHR, GPER1 | MEN1 3323/4885KMT2A 1555/4885TDP1 4081/4885 |
| US-20080293665-A1 | Purine Nucleotide Derivatives | CGAS, PDE8A, PDE7A | MEN1 634/4885KMT2A 2101/4885TDP1 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.