Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989397 | 0.89 | PTGS2 (0.64) | PTGS2MEN1KMT2AABCG2KDM4E | |
| SCHEMBL10985039 | 0.85 | MAPT (0.69) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10990122 | 0.84 | MEN1 (0.61) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10515711 | 0.84 | MEN1 (0.65) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1499605 | 0.84 | PTGS2 (0.59) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1499413 | 0.83 | PTGS2 (0.61) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28689403 | 0.83 | MT-CO2 (0.72) | PTGS2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12767204 | 0.82 | KMT2A (0.65) | PTGS2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28676345 | 0.82 | MEN1 (0.72) | PTGS2MEN1KMT2AABCG2KDM4E | |
| SCHEMBL10988985 | 0.82 | ALDH1A1 (0.63) | PTGS2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |