SCHEMBL28689403

SCHEMBL28689403

COc1ccc(CNC(=O)c2ccccc2Nc2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MT-CO2 P00403 3/20 0.72
MAPT P10636 4/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
HPGD P15428 5/20 0.62
NPC1 O15118 3/20 0.60
RAB9A P51151 2/20 0.60
PTGS2 P35354 2/20 0.57
TP53 P04637 1/20 0.56
GLA P06280 1/20 0.56
PTGS1 P23219 1/20 0.55
PPARG P37231 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NR2E3 Q9Y5X4 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10985039 0.95 MAPT (0.69) MT-CO2MAPTMEN1KMT2AHPGD
SCHEMBL28670756 0.88 MT-CO2 (0.73) MT-CO2MEN1KMT2ANPC1RAB9A
SCHEMBL5357501 0.86 MT-CO2 (0.83) MT-CO2MEN1KMT2AHPGDPTGS2
SCHEMBL28667666 0.85 MT-CO2 (0.63) MT-CO2MAPTMEN1KMT2AHPGD
SCHEMBL28674998 0.84 MT-CO2 (1.00) MT-CO2MEN1KMT2AHPGDPTGS2
SCHEMBL10985012 0.83 PTGS2 (0.60) MT-CO2MAPTMEN1KMT2AHPGD
SCHEMBL16127889 0.82 APEX1 (0.77) MAPTMEN1KMT2AHPGDNPC1
SCHEMBL28676345 0.81 MEN1 (0.72) MT-CO2MAPTMEN1KMT2AHPGD
SCHEMBL28667602 0.81 MT-CO2 (0.78) MT-CO2MAPTMEN1KMT2AHPGD
SCHEMBL10990122 0.81 MEN1 (0.61) MT-CO2MAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651768-A N-aryl anthranilamide compound and preparation and application thereof 南华大学 2021-11-16 CN disclosed