Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994663 | 0.87 | ALDH1A1 (0.39) | MAPTKDM4EPOLBNPSR1L3MBTL1 | |
| SCHEMBL10990185 | 0.81 | POLB (0.41) | MAPTKDM4EPOLBNPSR1L3MBTL1 | |
| SCHEMBL11367336 | 0.75 | ALDH1A1 (0.40) | MAPTPOLBNPSR1L3MBTL1HPGD | |
| SCHEMBL10985357 | 0.74 | TSHR (0.35) | OPRK1MAPTKDM4EPOLBNPSR1 | |
| SCHEMBL10992106 | 0.74 | MEN1 (0.48) | MAPTKDM4ENPSR1L3MBTL1HPGD | |
| SCHEMBL11369619 | 0.71 | POLB (0.42) | KDM4EPOLBNPSR1L3MBTL1HPGD | |
| SCHEMBL11361250 | 0.69 | ALDH1A1 (0.43) | MAPTKDM4EPOLBNPSR1L3MBTL1 | |
| SCHEMBL11361649 | 0.68 | ALDH1A1 (0.43) | MAPTKDM4EPOLBNPSR1HPGD | |
| SCHEMBL11367971 | 0.68 | POLB (0.45) | MAPTPOLBL3MBTL1HPGDLMNA | |
| SCHEMBL11377070 | 0.68 | POLB (0.45) | MAPTPOLBL3MBTL1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4561880-A | 1H[1,2,4]-Triazolo[1,2-a]pyridazine-1,3-diones useful as herbicides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0104484-A1 | A heterocyclic compound and its use as herbicide | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |