Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 5/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544058 | 0.79 | KCNA3 (0.67) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL4647042 | 0.79 | KCNA3 (0.67) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL8955863 | 0.79 | KCNA3 (0.67) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL6438840 | 0.79 | KCNA3 (0.67) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL1007097 | 0.79 | KCNA3 (0.67) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL28859138 | 0.78 | HTR1B (0.53) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL6272756 | 0.77 | KCNA3 (0.69) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL9700638 | 0.76 | CNR2 (0.58) | CNR2CNR1KCNA3HTR1BHTR1D | |
| SCHEMBL8955424 | 0.76 | TDP1 (0.67) | CNR2HTR1DTDP1TP53CYP1A2 | |
| SCHEMBL27904038 | 0.76 | TDP1 (0.67) | CNR2HTR1DTDP1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536503-A | Naphthoxyalkylamines and related compounds as antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0082005-A2 | Naphthoxyalkylamines and related compounds, their preparation and antiinflammatory compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-06-22 | — | — | EP | disclosed |