SCHEMBL9736604

SCHEMBL9736604

CCS(=O)(=O)c1nnc(Cl)s1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.36
CA2 P00918 3/20 0.35
ALDH1A1 P00352 4/20 0.33
KMT2A Q03164 2/20 0.33
FBP1 P09467 1/20 0.33
MEN1 O00255 1/20 0.33
CA1 P00915 2/20 0.32
CA4 P22748 2/20 0.32
CA9 Q16790 2/20 0.32
HSD11B1 P28845 1/20 0.31
MAPT P10636 1/20 0.30
LMNA P02545 1/20 0.30
HTR1A P08908 1/20 0.30
HTR2A P28223 1/20 0.30
HTR7 P34969 1/20 0.30
HTR6 P50406 1/20 0.30
CA12 O43570 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10987136 0.84 CA2 (0.41) RXFP1CA2KMT2AMEN1CA1
SCHEMBL11151902 0.83 HPGD (0.34) CA2ALDH1A1KMT2AMEN1MAPT
SCHEMBL9508988 0.77 CA1 (0.47) CA2ALDH1A1FBP1CA1CA4
SCHEMBL9742055 0.76 ALDH1A1 (0.44) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL11703035 0.75 CA2 (0.33) CA2CA1CA4CA9
SCHEMBL9871955 0.75 RECQL (0.42) RXFP1CA2ALDH1A1KMT2AMEN1
SCHEMBL9860007 0.74 CA2 (0.59) CA2ALDH1A1CA1CA4CA9
SCHEMBL11706188 0.71 CA2 (0.37) CA2ALDH1A1KMT2ACA1CA4
SCHEMBL11387456 0.69 CA2 (0.36) RXFP1CA2KMT2AMEN1CA1
SCHEMBL11390911 0.69 CA2 (0.36) CA2CA1CA4CA9CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096483-A Post- and preemergence; rice, soybeans, cereals, cotton, sugar beet BAYER AKTIENGESELLSCHAFT (DE) 1992-03-17 US disclosed
EP-0192117-B1 5-CHLORO-1,3,4-THIADIAZOL-2-YLOXY-ACETAMIDES BAYER AG (DE) 1990-09-26 EP disclosed
EP-0192117-A2 5-Chloro-1,3,4-thiadiazol-2-yloxy-acetamides BAYER AG (DE) 1986-08-27 EP disclosed