Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10987136 | 0.80 | CA2 (0.41) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL9860007 | 0.71 | CA2 (0.59) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL9736604 | 0.71 | RXFP1 (0.36) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL11387456 | 0.71 | CA2 (0.36) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL11377949 | 0.69 | CA2 (0.38) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL11703035 | 0.68 | CA2 (0.33) | CA2CA1CA4CA9 | |
| SCHEMBL11382889 | 0.67 | CA2 (0.33) | CA2CA1CA4ALDH1A1POLB | |
| SCHEMBL11389798 | 0.67 | CA2 (0.36) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL10981850 | 0.67 | CA2 (0.51) | CA2CA1CA4CA5ACA5B | |
| SCHEMBL11390911 | 0.67 | CA2 (0.36) | CA2CA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061645-A | FUNGICIDE, NEMATOCIDE | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |
| US-4005213-A | 2,5-Substituted-1,3,4-thiadiazoles as fungicides | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |