Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10987263 | 0.89 | MAPT (0.51) | MAPTALOX15FABP4ADRA1DADRA1A | |
| SCHEMBL10839355 | 0.88 | ADRA1A (0.52) | MAPTALOX15FABP4ADRA1DADRA1A | |
| SCHEMBL10988251 | 0.86 | MEN1 (0.53) | MAPTALOX15MEN1KMT2ATSHR | |
| SCHEMBL10992166 | 0.82 | TP53 (0.53) | MAPTALOX15FABP4ADRA1DADRA1A | |
| SCHEMBL27752030 | 0.81 | ADRA1A (0.57) | MAPTADRA1DADRA1AADRA1BABCC1 | |
| SCHEMBL10837593 | 0.81 | ADRA1A (0.56) | MAPTALOX15ADRA1DADRA1AADRA1B | |
| SCHEMBL28454648 | 0.80 | ADRA1A (0.59) | MAPTFABP4ADRA1DADRA1AADRA1B | |
| Fenamic Acid SCHEMBL28097929 | 0.80 | FABP4 (0.79) | MAPTALOX15FABP4MEN1KMT2A | |
| SCHEMBL10992103 | 0.79 | MEN1 (0.49) | MAPTALOX15ADRA1AMEN1KMT2A | |
| SCHEMBL29822323 | 0.78 | TP53 (0.69) | MAPTADRA1DADRA1AADRA1BABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312209-B2 | Acridone inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |