Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988258 | 1.00 | OPRD1 (0.42) | OPRD1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL7359022 | 0.81 | OPRD1 (0.45) | OPRD1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL11148240 | 0.70 | OPRD1 (0.42) | OPRD1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL28003654 | 0.68 | ALDH1A1 (0.46) | OPRD1ALDH1A1HPGDTSHRLMNA | |
| SCHEMBL31696327 | 0.68 | HDAC3 (0.46) | OPRD1NPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL28003655 | 0.68 | ALDH1A1 (0.46) | OPRD1ALDH1A1HPGDTSHRLMNA | |
| SCHEMBL8347428 | 0.67 | TBXAS1 (0.68) | LMNAMEN1KMT2ACYP2D6CYP3A4 | |
| SCHEMBL8347430 | 0.67 | TBXAS1 (0.68) | LMNAMEN1KMT2ACYP2D6CYP3A4 | |
| SCHEMBL6209007 | 0.66 | KDM4E (0.48) | NPC1RAB9ATDP1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28253387 | 0.66 | TBXAS1 (0.69) | LMNACYP2D6CYP3A4MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492692-A | BACTERICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | disclosed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | disclosed |