Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446079 | 0.88 | KCNH2 (0.43) | OPRD1POLBALDH1A1KMT2ALMNA | |
| SCHEMBL11147547 | 0.87 | BTK (0.40) | BTKPOLBMEN1ALDH1A1KMT2A | |
| SCHEMBL11155733 | 0.86 | OPRD1 (0.37) | OPRD1PPARGPPARAPOLBLMNA | |
| SCHEMBL11147568 | 0.83 | BTK (0.39) | BTKMEN1KMT2ANPC1LMNA | |
| SCHEMBL11148693 | 0.79 | KCNH2 (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL11148698 | 0.79 | KCNH2 (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL11440320 | 0.79 | TDP1 (0.41) | OPRD1POLBMEN1KMT2ALMNA | |
| SCHEMBL11148132 | 0.77 | POLB (0.44) | BTKPOLBMEN1KMT2ANPC1 | |
| SCHEMBL11439870 | 0.76 | KCNH2 (0.39) | POLBALDH1A1KMT2ALMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11433492 | 0.76 | POLB (0.43) | BTKPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009683-B1 | BASIC PHENYL ETHERS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE PREPARATION OF THESE ETHERS AND COMPOSITIONS | MERCK PATENT GmbH (DE) | 1983-08-10 | — | — | EP | disclosed |
| EP-0009683-A1 | Basic phenyl ethers, pharmaceutical compositions containing them and the preparation of these ethers and compositions | MERCK PATENT GmbH (DE) | 1980-04-16 | — | — | EP | disclosed |