SCHEMBL10990804

SCHEMBL10990804

CCOC(=O)N(CCN(C(=O)OCC)C1CCCCC1)CCN(C(=O)OCC)C1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 4/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.36
HSD17B10 Q99714 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ATM Q13315 2/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP6 P55212 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10988348 0.93 ALDH1A1 (0.44) ALDH1A1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL13462953 0.83 ALDH1A1 (0.50) ALDH1A1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL1837926 0.83 ALDH1A1 (0.44) ALDH1A1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL20165446 0.83 L3MBTL1 (0.43) ALDH1A1L3MBTL1KDM4ENPC1LMNA
SCHEMBL31126845 0.80 CYP1A2 (0.41) ALDH1A1L3MBTL1KDM4ENPC1SMN1; SMN2
SCHEMBL4460610 0.80 CYP1A2 (0.41) ALDH1A1L3MBTL1SMN1; SMN2ATMTHRB
SCHEMBL20166075 0.79 L3MBTL1 (0.41) ALDH1A1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL24661783 0.79 PYGL (0.42) ALDH1A1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL28488966 0.78 NAAA (0.49) ALDH1A1L3MBTL1KDM4EMEN1KMT2A
SCHEMBL13434171 0.78 SLC6A4 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4525503-A POLYETHYLENE, POLYPROPYLENE CIBA-GEIGY S.P.A. (IT) 1985-06-25 US disclosed
US-4501837-A LIGHT, HEAT, AND OXIDATION STABILIZERS CIBA-GEIGY S.P.A. (IT) 1985-02-26 US disclosed
US-4369321-A Piperidine derivatives which are stabilizers for synthetic polymers CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1983-01-18 US disclosed