Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360314 | 0.98 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| Water SCHEMBL1360217 | 0.95 | MAPK1 (0.56) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL13270530 | 0.86 | TNFRSF1A (0.47) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL222221 | 0.84 | ALDH1A1 (0.74) | MAPK1ALDH1A1TDP1TNFRSF1AMAPT | |
| Water SCHEMBL11592742 | 0.82 | ALDH1A1 (0.70) | MAPK1ALDH1A1TDP1TNFRSF1AMAPT | |
| Water SCHEMBL11592745 | 0.82 | ALDH1A1 (0.70) | MAPK1ALDH1A1TDP1TNFRSF1AMAPT | |
| SCHEMBL8923089 | 0.81 | MAPT (0.46) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL6989990 | 0.80 | TNFRSF1A (0.72) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL6989989 | 0.80 | TNFRSF1A (0.72) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL4214525 | 0.78 | TNFRSF1A (0.57) | MAPK1TNFRSF1ACES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |