Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922721 | 0.84 | ALDH1A1 (0.52) | MAPTALDH1A1MAPK1TDP1ATM | |
| SCHEMBL360314 | 0.83 | MAPK1 (0.58) | MAPTCYP1A2CYP2C19TNFRSF1AALDH1A1 | |
| SCHEMBL8923151 | 0.83 | F3 (0.51) | MAPTCYP1A2CYP2C19TNFRSF1AALDH1A1 | |
| Phenylglyoxal SCHEMBL8924305 | 0.82 | TDP1 (0.67) | MAPTTNFRSF1AALDH1A1MAPK1TDP1 | |
| Water SCHEMBL1360217 | 0.81 | MAPK1 (0.56) | MAPTCYP1A2CYP2C19TNFRSF1AALDH1A1 | |
| SCHEMBL10991995 | 0.81 | MAPK1 (0.56) | MAPTCYP1A2CYP2C19TNFRSF1AALDH1A1 | |
| SCHEMBL8923535 | 0.78 | MAOB (0.50) | MAPTALDH1A1MAPK1TDP1SMN1; SMN2 | |
| SCHEMBL13270530 | 0.77 | TNFRSF1A (0.47) | MAPTCYP1A2CYP2C19TNFRSF1AALDH1A1 | |
| SCHEMBL222221 | 0.72 | ALDH1A1 (0.74) | MAPTCYP1A2CYP2C19TNFRSF1AALDH1A1 | |
| SCHEMBL6099699 | 0.71 | L3MBTL1 (0.49) | MAPTALDH1A1MAPK1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610016-A | REACTING A GLYOXAL DERIVATIVE, CHEMILUMINESCENCE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0675360-A2 | Method for measuring adenyl group containing substances using heteropoly acid | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |