Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1360217 | 0.98 | MAPK1 (0.56) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL10991995 | 0.98 | MAPK1 (0.56) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL13270530 | 0.88 | TNFRSF1A (0.47) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL222221 | 0.87 | ALDH1A1 (0.74) | MAPK1ALDH1A1TDP1TNFRSF1AMAPT | |
| Water SCHEMBL11592745 | 0.84 | ALDH1A1 (0.70) | MAPK1ALDH1A1TDP1TNFRSF1AMAPT | |
| Water SCHEMBL11592742 | 0.84 | ALDH1A1 (0.70) | MAPK1ALDH1A1TDP1TNFRSF1AMAPT | |
| SCHEMBL8923089 | 0.83 | MAPT (0.46) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL6989990 | 0.82 | TNFRSF1A (0.72) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL6989989 | 0.82 | TNFRSF1A (0.72) | MAPK1ALDH1A1TDP1TNFRSF1ACES2 | |
| SCHEMBL4214525 | 0.80 | TNFRSF1A (0.57) | MAPK1TNFRSF1ACES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894870-B | Polymer and polymer nanoparticle of benzobisquinoxaline receptor for photothermal therapy, and preparation and application thereof | 华南理工大学 | 2024-06-25 | — | — | CN | claimed |
| CN-115894870-A | Polymer and polymer nanoparticle of benzo-bis-quinoxaline receptor for photothermal therapy, and preparation and application thereof | 华南理工大学 | 2023-04-04 | — | — | CN | claimed |
| US-20220290106-A1 | Method for Promoting Cell Proliferation, and Method for Preparing Cell Cluster | OSAKA UNIVERSITY (JP) | 2022-09-15 | — | — | US | claimed |
| EP-3998333-A1 | METHOD FOR PROMOTING CELL PROLIFERATION, AND METHOD FOR PREPARING CELL CLUSTER | Osaka University (JP) | 2022-05-18 | — | — | EP | claimed |
| WO-2021006346-A1 | METHOD FOR PROMOTING CELL PROLIFERATION, AND METHOD FOR PREPARING CELL CLUSTER | 国立大学法人大阪大学 | 2021-01-14 | — | — | WO | claimed |
| US-20130189245-A1 | METHOD FOR PRODUCING TOXOIDS USING ALPHA-DICARBONYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2013-07-25 | — | — | US | claimed |
| EP-2593132-A2 | METHOD FOR PRODUCING TOXOIDS USING ALPHA - DICARBONYL COMPOUNDS& xA; | The Secretary of State for Defence (GB) | 2013-05-22 | — | — | EP | claimed |
| CN-103079590-A | Method for producing toxoids using alpha - dicarbonyl compounds | SECR DEFENCE | 2013-05-01 | — | — | CN | claimed |
| WO-2012007728-A2 | TOXOIDING METHOD | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2012-01-19 | — | — | WO | claimed |
| US-6130331-A | Chemical synthesis of a chiral 1,4-oxazin-2-one | MERCK SHARP & DOHME LTD. (GB) | 2000-10-10 | — | — | US | claimed |
| US-5610016-A | REACTING A GLYOXAL DERIVATIVE, CHEMILUMINESCENCE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-11 | — | — | US | claimed |
| EP-0675360-A2 | Method for measuring adenyl group containing substances using heteropoly acid | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-04 | — | — | EP | claimed |
| EP-4598923-A1 | SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS | The Regents of the University of California (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024210572-A1 | NOVEL IMIDAZOLE DERIVATIVE AND USE THEREOF | 주식회사 펠레메드 | 2024-10-10 | — | — | WO | disclosed |
| US-12054472-B2 | 1,2,4-triazine-4-amine derivatives | NXERA PHARMA UK LIMITED (GB) | 2024-08-06 | — | — | US | disclosed |
| CN-115894870-B | Polymer and polymer nanoparticle of benzobisquinoxaline receptor for photothermal therapy, and preparation and application thereof | 华南理工大学 | 2024-06-25 | — | — | CN | disclosed |
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0137333-A2 | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase | ALCON LABORATORIES, INC. (US) | 1985-04-17 | — | — | EP | disclosed |
| US-4159375-A | 6- AND 7-Aryl-1,2,4-triazolo[4,3-b]-1,2,4-triazines | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4046763-A | INTERMEDIATE FOR ULTRAVIOLET LIGHT ABSORBERS | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12054472-B2 | 1,2,4-triazine-4-amine derivatives | ADORA2A, ADORA2B, ADORA1 | MAPK1 2655/4885ALDH1A1 251/4885TDP1 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.