Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.58 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989990 | 1.00 | TNFRSF1A (0.72) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL6942827 | 0.91 | ALDH1A1 (0.67) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL6942832 | 0.91 | ALDH1A1 (0.67) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL28024599 | 0.88 | TNFRSF1A (0.64) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL6451968 | 0.88 | TNFRSF1A (0.64) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL9798239 | 0.86 | TNFRSF1A (0.62) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL9798236 | 0.86 | TNFRSF1A (0.62) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL20273264 | 0.86 | TNFRSF1A (0.62) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL956091 | 0.86 | CYP1A2 (0.63) | TNFRSF1ACYP1A2CYP2C19CES2CES1 | |
| SCHEMBL956092 | 0.86 | CYP1A2 (0.63) | TNFRSF1ACYP1A2CYP2C19CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740640-B1 | DIBENZODIAZOCINE POLYMERS | SOLVAY SPECIALTY POLYMERS USA L L C (US) | 2012-06-13 | — | — | EP | disclosed |
| US-7238771-B2 | Dibenzodiazocine polymers | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238771-B2 | Dibenzodiazocine polymers | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2007-07-03 | — | — | US | disclosed |
| EP-0921119-B1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-07-02 | — | — | EP | disclosed |
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0921119-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-06-09 | — | — | EP | disclosed |