Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21134659 | 0.94 | CHRNB2 (0.37) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19628592 | 0.92 | CHRNB2 (0.36) | CHRNB2CHRNA7CHRNA4LMNADPP4 | |
| SCHEMBL16382235 | 0.90 | CHRNB2 (0.38) | CHRNB2CHRNA7CHRNA4LMNADPP4 | |
| SCHEMBL12717785 | 0.88 | CHRNB2 (0.42) | CHRNB2CHRNA7CHRNA4LMNADPP4 | |
| SCHEMBL12717782 | 0.86 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4LMNADPP4 | |
| SCHEMBL22784190 | 0.83 | CHRNB2 (0.35) | CHRNB2CHRNA7CHRNA4LMNACHRNB4 | |
| SCHEMBL12718160 | 0.82 | METAP2 (0.34) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL12718156 | 0.82 | METAP2 (0.34) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL9689082 | 0.81 | CHRNB2 (0.60) | CHRNB2CHRNA7CHRNA4DPP4CHRNB4 | |
| SCHEMBL2477311 | 0.81 | GNAO1 (0.34) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4526969-A | Trifluoromethyl substituted perfluoro quinolizines | THE GREEN CROSS CORPORATION (JP) | 1985-07-02 | — | — | US | disclosed |