Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382235 | 0.94 | CHRNB2 (0.38) | CHRNB2CHRNA7CHRNA4PSEN1PSEN2 | |
| SCHEMBL12717782 | 0.94 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4PSEN1PSEN2 | |
| SCHEMBL21134659 | 0.94 | CHRNB2 (0.37) | CHRNB2CHRNA7CHRNA4PSEN1PSEN2 | |
| SCHEMBL10992013 | 0.92 | CHRNB2 (0.39) | CHRNB2CHRNA7CHRNA4LMNADPP4 | |
| SCHEMBL12717785 | 0.92 | CHRNB2 (0.42) | CHRNB2CHRNA7CHRNA4PSEN1PSEN2 | |
| SCHEMBL9689054 | 0.86 | CHRNB2 (0.50) | CHRNB2CHRNA7CHRNA4S1PR1S1PR3 | |
| SCHEMBL12718156 | 0.86 | METAP2 (0.34) | CHRNB2CHRNA7CHRNA4PSEN1PSEN2 | |
| SCHEMBL12718160 | 0.86 | METAP2 (0.34) | CHRNB2CHRNA7CHRNA4PSEN1PSEN2 | |
| SCHEMBL2477311 | 0.85 | GNAO1 (0.34) | CHRNB2CHRNA7CHRNA4PSEN1PSEN2 | |
| SCHEMBL10861805 | 0.83 | KMT2A (0.33) | CHRNB2CHRNA7CHRNA4LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334831-A1 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334831-A1 | Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof | CYP8B1, CYP3A5, HRH4 | CHRNB2 247/4885CHRNA7 801/4885CHRNA4 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.