Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988251 | 0.92 | MEN1 (0.53) | MEN1KMT2AMAPTALOX12MAPK1 | |
| SCHEMBL10992166 | 0.86 | TP53 (0.53) | MEN1KMT2ATP53ADRA1AMAPT | |
| SCHEMBL10982132 | 0.84 | MEN1 (0.52) | MEN1KMT2AADRA1AMAPTALOX12 | |
| SCHEMBL10837593 | 0.82 | ADRA1A (0.56) | MEN1KMT2ATP53ADRA1AMAPT | |
| SCHEMBL10983702 | 0.80 | MEN1 (0.56) | MEN1KMT2AMAPTALOX12MAPK1 | |
| SCHEMBL14349252 | 0.79 | MAPT (0.57) | MEN1KMT2ATP53ADRA1AMAPT | |
| SCHEMBL10987263 | 0.78 | MAPT (0.51) | MEN1KMT2ATP53ADRA1AMAPT | |
| SCHEMBL1499605 | 0.76 | PTGS2 (0.59) | MEN1KMT2ALMNAPTGS2ALDH1A1 | |
| SCHEMBL10989397 | 0.76 | PTGS2 (0.64) | MEN1KMT2ATP53MAPTALOX12 | |
| SCHEMBL10935935 | 0.76 | MEN1 (0.60) | MEN1KMT2AMAPTALOX12MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |