Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974092 | 0.86 | POLQ (0.46) | POLQSIGMAR1HDAC1HDAC8ANO1 | |
| SCHEMBL10973368 | 0.85 | POLQ (0.45) | POLQSIGMAR1HDAC1HDAC8ANO1 | |
| SCHEMBL8568288 | 0.85 | POLQ (0.55) | POLQSIGMAR1HDAC1HDAC8ANO1 | |
| SCHEMBL10931655 | 0.84 | ALDH1A1 (0.46) | POLQSIGMAR1HDAC1HDAC8ANO1 | |
| SCHEMBL10995737 | 0.83 | ALDH1A1 (0.47) | POLQSIGMAR1HDAC1HDAC8ANO1 | |
| SCHEMBL19751892 | 0.82 | POLQ (0.52) | POLQSIGMAR1HDAC1HDAC8ANO1 | |
| SCHEMBL10931630 | 0.80 | SIGMAR1 (0.41) | POLQSIGMAR1HDAC1HDAC8ANO1 | |
| SCHEMBL10993899 | 0.79 | NPC1 (0.47) | ALDH1A1HPGDGAASMN1; SMN2HTT | |
| SCHEMBL10997197 | 0.78 | GLS (0.57) | ALDH1A1HTTKMT2AKCNJ5KCNJ3 | |
| SCHEMBL29907879 | 0.77 | POLQ (0.53) | POLQSIGMAR1HDAC1HDAC8ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544670-A | ANTIPROTOZOA AGENTS, GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | WILLIAM H. RORER, INC. (US) | 1985-10-01 | — | — | US | disclosed |