Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5437451 | 0.82 | MAPT (0.44) | MAPTALDH1A1KDM4EHPGDPDE3B | |
| SCHEMBL13931143 | 0.76 | MAPT (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4187132 | 0.70 | GSTP1 (0.53) | MAPTALDH1A1KDM4EPDE3BPDE3A | |
| SCHEMBL9466940 | 0.69 | MAPT (0.45) | L3MBTL1MAPTALDH1A1KDM4EGLA | |
| SCHEMBL721861 | 0.69 | ACHE (0.65) | L3MBTL1MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL6003729 | 0.65 | SIGMAR1 (0.38) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11000171 | 0.64 | AHR (0.43) | MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL4603359 | 0.64 | MAPT (0.49) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28830721 | 0.64 | BACE1 (0.56) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7349003 | 0.63 | CYP19A1 (0.48) | L3MBTL1MAPTALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529736-A | Antidepressant | AMERICAN CYANAMID COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0100426-A1 | 3a-(substituted-phenyl)-hexaloctahydro-4,7-alkanoisoindoles | AMERICAN CYANAMID COMPANY (US) | 1984-02-15 | — | — | EP | disclosed |