Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 5/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994616 | 0.93 | GRM5 (0.49) | GRM5PDK1PDK2PDK3PDK4 | |
| SCHEMBL10998809 | 0.92 | GRM5 (0.45) | GRM5GAANLRP3POLBTNKS2 | |
| SCHEMBL10993445 | 0.88 | GRM5 (0.45) | GRM5GAANLRP3POLB | |
| SCHEMBL10998555 | 0.88 | NLRP3 (0.44) | GRM5NLRP3POLB | |
| SCHEMBL10992667 | 0.86 | GRM5 (0.43) | GRM5PDK1PDK2PDK3PDK4 | |
| SCHEMBL10992172 | 0.85 | GRM5 (0.63) | GRM5MAPK14PDK1PDK2PDK3 | |
| SCHEMBL10992189 | 0.85 | GRM5 (0.63) | GRM5MAPK14PDK1PDK2PDK3 | |
| SCHEMBL10992675 | 0.85 | DRD4 (0.41) | GRM5DRD4NLRP3TNKS2 | |
| SCHEMBL11000472 | 0.84 | GRM5 (0.39) | GRM5GAANLRP3POLBTNKS2 | |
| SCHEMBL10993280 | 0.81 | GRM5 (0.44) | GRM5GAAPOLBTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | disclosed |