Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27836650 | 0.78 | LMNA (0.52) | L3MBTL1LMNAALDH1A1HPGDHDAC6 | |
| SCHEMBL22072300 | 0.78 | LMNA (0.49) | L3MBTL1LMNAALDH1A1HPGDMETAP2 | |
| SCHEMBL28154646 | 0.76 | LMNA (0.51) | L3MBTL1LMNAALDH1A1HPGDHDAC6 | |
| SCHEMBL18526138 | 0.76 | ALDH1A1 (0.50) | L3MBTL1LMNAALDH1A1HPGDRAB9A | |
| SCHEMBL5821276 | 0.75 | LMNA (0.60) | L3MBTL1LMNAEGLN1ALDH1A1HDAC6 | |
| SCHEMBL7347726 | 0.75 | ALDH1A1 (0.46) | L3MBTL1LMNAALDH1A1HPGDMAPT | |
| SCHEMBL22918322 | 0.75 | EGLN1 (0.74) | L3MBTL1LMNAEGLN1ALDH1A1HDAC6 | |
| SCHEMBL7958550 | 0.74 | ALDH1A1 (0.55) | L3MBTL1LMNAALDH1A1HPGDTSHR | |
| SCHEMBL17420660 | 0.74 | ALDH1A1 (0.49) | L3MBTL1LMNAALDH1A1HPGDRAB9A | |
| SCHEMBL4454368 | 0.72 | L3MBTL1 (0.41) | L3MBTL1LMNAEGLN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4530931-A | 8-Quinoline carbanilates for the inhibition of lipolysis | USV PHARMACEUTICAL CORP. (US) | 1985-07-23 | — | — | US | disclosed |