Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997158 | 1.00 | GRM5 (0.56) | GRM5NLRP3HTTMEN1KMT2A | |
| SCHEMBL10995246 | 0.93 | GRM5 (0.60) | GRM5NLRP3HTTMEN1KMT2A | |
| SCHEMBL10995242 | 0.93 | GRM5 (0.60) | GRM5NLRP3HTTMEN1KMT2A | |
| SCHEMBL10993124 | 0.90 | GRM5 (0.62) | GRM5HTTMEN1KMT2APOLB | |
| SCHEMBL10993126 | 0.90 | GRM5 (0.62) | GRM5HTTMEN1KMT2APOLB | |
| SCHEMBL10998555 | 0.87 | NLRP3 (0.44) | GRM5NLRP3HTTMEN1KMT2A | |
| SCHEMBL10992172 | 0.85 | GRM5 (0.63) | GRM5POLBRAB9A | |
| SCHEMBL10992189 | 0.85 | GRM5 (0.63) | GRM5POLBRAB9A | |
| SCHEMBL10991240 | 0.83 | GRM5 (0.55) | GRM5MEN1KMT2ANPSR1POLB | |
| SCHEMBL10990477 | 0.82 | GRM5 (0.54) | GRM5NLRP3MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4542144-A | EPILEPSY | MCNEILAB INC. (US) | 1985-09-17 | — | — | US | claimed |