Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994835 | 0.85 | TSHR (0.33) | KMT2AMEN1 | |
| SCHEMBL10992228 | 0.83 | SLC6A2 (0.40) | KMT2AMEN1POLBMAPT | |
| SCHEMBL7440923 | 0.80 | THRA (0.37) | KMT2AMEN1ITGB3ITGA2BTHRA | |
| SCHEMBL10993172 | 0.80 | ALDH1A1 (0.36) | THRBRAB9A | |
| SCHEMBL10992659 | 0.80 | SLC6A2 (0.37) | — | |
| SCHEMBL10992177 | 0.78 | SMN1; SMN2 (0.35) | MAPT | |
| SCHEMBL10995194 | 0.78 | ALDH1A1 (0.44) | KMT2AMAPT | |
| SCHEMBL10989799 | 0.78 | IDO1 (0.34) | MAPT | |
| SCHEMBL10996527 | 0.77 | BAX (0.30) | — | |
| SCHEMBL7440201 | 0.77 | ADRB2 (0.38) | KMT2AMEN1ITGB3ITGA2BTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |