Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440923 | 0.96 | THRA (0.37) | ADRB2ADRB1ADRB3THRATHRB | |
| SCHEMBL7446282 | 0.88 | LMNA (0.41) | ADRB2ADRB1ADRB3KMT2ASMN1; SMN2 | |
| SCHEMBL7435145 | 0.85 | KDM4E (0.35) | ADRB2ADRB1ITGB3ITGA2BKMT2A | |
| SCHEMBL7434523 | 0.85 | GNAI3 (0.31) | ADRB2ADRB1SLC6A4 | |
| SCHEMBL7436853 | 0.84 | MTNR1A (0.43) | KMT2ASMN1; SMN2MTNR1AFFAR1 | |
| SCHEMBL7433144 | 0.83 | ADRB2 (0.35) | ADRB2ADRB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7436499 | 0.81 | GNAI3 (0.30) | — | |
| SCHEMBL7435716 | 0.81 | PNMT (0.33) | THRBITGB3ITGA2BKDM4EITGAV | |
| SCHEMBL7431324 | 0.81 | CA2 (0.38) | ADRB2ADRB1KMT2AMAPTKDM4E | |
| SCHEMBL7435524 | 0.81 | CA2 (0.38) | ADRB2ADRB1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |