Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 5/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984635 | 0.95 | CYP1A2 (0.59) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL13633202 | 0.90 | HTR1B (0.66) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6071440 | 0.88 | HTR1B (0.64) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL6318521 | 0.84 | HTR1B (0.73) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL10989798 | 0.84 | DRD2 (0.57) | HTR1BCYP1A2CYP3A4TSHRDRD2 | |
| SCHEMBL10987189 | 0.80 | SLC6A4 (0.58) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL7908960 | 0.80 | HTR1B (0.69) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL18551224 | 0.79 | HRH1 (0.62) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL7060492 | 0.79 | HRH1 (0.62) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL10983235 | 0.79 | SLC6A4 (0.56) | HTR1BHRH1SLC6A4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562211-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | claimed |
| JP-54126732-A | — | — | None | — | — | JP | disclosed |
| US-4562211-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | disclosed |
| JP-S54126732-A | ANTIDEPRESSANT CONTAINING 2-(3-AMINOPROPOXY)DIPHENYL ETHER OR ITS DERIVATIVE | MITSUBISHI CHEM IND LTD | 1979-10-02 | — | — | JP | disclosed |