Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 4/20 | 0.53 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993201 | 0.95 | HTR1B (0.58) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| SCHEMBL10987189 | 0.85 | SLC6A4 (0.58) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| SCHEMBL13633202 | 0.84 | HTR1B (0.66) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| SCHEMBL10983235 | 0.84 | SLC6A4 (0.56) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6071440 | 0.83 | HTR1B (0.64) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| SCHEMBL11725212 | 0.82 | HTR1B (0.61) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| SCHEMBL11726058 | 0.81 | L3MBTL1 (0.59) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| SCHEMBL10984130 | 0.79 | L3MBTL1 (0.75) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11727118 | 0.79 | LMNA (0.60) | CYP1A2CYP3A4TSHRTP53L3MBTL1 | |
| SCHEMBL10989798 | 0.79 | DRD2 (0.57) | CYP1A2CYP3A4TSHRL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562211-A | ANTIDEPRESSANTS | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | disclosed |