Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910364 | 0.89 | NPC1 (0.53) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11033417 | 0.79 | PTGIR (0.44) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL18770386 | 0.74 | ERN1 (0.52) | NPC1RAB9AMEN1KMT2AMAPK1 | |
| SCHEMBL12806594 | 0.74 | LTA4H (0.57) | LTA4HNPC1RAB9APARP10TUBB4A | |
| SCHEMBL23074268 | 0.72 | LTA4H (1.00) | LTA4HPARP10MEN1KMT2AALDH1A1 | |
| SCHEMBL3415262 | 0.72 | LTA4H (1.00) | LTA4HPARP10MEN1KMT2AALDH1A1 | |
| SCHEMBL10596186 | 0.72 | NPC1 (0.61) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24068857 | 0.72 | TYR (0.80) | LTA4HNPC1RAB9APARP10TRIM24 | |
| SCHEMBL11508000 | 0.71 | CA12 (0.43) | NPC1RAB9AMEN1KMT2AMAPK1 | |
| SCHEMBL910590 | 0.71 | CES2 (0.44) | MEN1KMT2ATYRALDH1A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |