Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885042 | 0.82 | NCF1 (0.48) | KMT2A | |
| SCHEMBL6066269 | 0.77 | ALDH1A1 (0.32) | CYP2C9KMT2A | |
| SCHEMBL10993207 | 0.76 | SMPD3 (0.36) | CLK2CLK3DYRK1ANPY5R | |
| SCHEMBL10997674 | 0.76 | MAPT (0.40) | KMT2A | |
| SCHEMBL2885736 | 0.74 | MAP4K4 (0.45) | KMT2A | |
| SCHEMBL2885749 | 0.73 | HTR1A (0.35) | — | |
| SCHEMBL6065199 | 0.72 | MEN1 (0.42) | SCN9AATMKMT2A | |
| SCHEMBL10993998 | 0.72 | CTSB (0.43) | CYP2C9KMT2A | |
| SCHEMBL31525814 | 0.70 | HTR1A (0.40) | CYP2C9MAT2A | |
| SCHEMBL5215349 | 0.69 | ALDH1A1 (0.41) | CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552879-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4399134-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |