Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.38 |
| ▸ | OGA | O60502 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995105 | 0.92 | CYP2D6 (0.35) | CYP2D6FFAR1 | |
| SCHEMBL10995041 | 0.89 | ALDH1A1 (0.36) | CYP2D6 | |
| SCHEMBL10996165 | 0.89 | TEAD1 (0.42) | TEAD1CYP2D6 | |
| SCHEMBL7436237 | 0.86 | TEAD1 (0.42) | TEAD1OGACCR3 | |
| SCHEMBL10991901 | 0.84 | LMNA (0.42) | CYP2D6 | |
| SCHEMBL10994531 | 0.83 | CA2 (0.34) | CYP2D6 | |
| SCHEMBL10993606 | 0.83 | TEAD1 (0.35) | TEAD1CYP2D6FFAR1 | |
| SCHEMBL10997571 | 0.83 | FFAR1 (0.34) | CYP2D6FFAR1 | |
| SCHEMBL10993683 | 0.82 | ALDH1A1 (0.37) | OGAMC4RFFAR1 | |
| SCHEMBL10991654 | 0.81 | CHRM2 (0.43) | CYP2D6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |