Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 10/20 | 0.42 |
| ▸ | OGA | O60502 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430176 | 0.90 | TEAD1 (0.44) | TEAD1OGAADRB1ADRB3 | |
| SCHEMBL7436565 | 0.89 | ALDH1A1 (0.39) | — | |
| SCHEMBL10994657 | 0.86 | TEAD1 (0.42) | TEAD1OGACCR3 | |
| SCHEMBL7443120 | 0.86 | LMNA (0.41) | ADRB1ADRB3 | |
| SCHEMBL7437018 | 0.84 | TSHR (0.32) | POLB | |
| SCHEMBL7442146 | 0.84 | EPHX1 (0.41) | TEAD1OGAEPHX1POLB | |
| SCHEMBL7434579 | 0.84 | CA2 (0.35) | — | |
| SCHEMBL7437302 | 0.83 | TEAD1 (0.35) | TEAD1OGATRPV1EPHX1 | |
| SCHEMBL7495730 | 0.82 | CA2 (0.36) | POLB | |
| SCHEMBL7433758 | 0.82 | NPC1 (0.38) | ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |