Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993684 | 0.91 | ALDH1A1 (0.48) | MAPTATMALDH1A1TSHRLMNA | |
| SCHEMBL10991244 | 0.88 | POLB (0.54) | MAPTATMALDH1A1TSHRLMNA | |
| SCHEMBL10995111 | 0.86 | LMNA (0.50) | MAPTALDH1A1TSHRLMNAUSP2 | |
| SCHEMBL10994841 | 0.85 | ALDH1A1 (0.43) | MAPTATMALDH1A1TSHRLMNA | |
| SCHEMBL10992935 | 0.85 | CYP3A4 (0.48) | ALDH1A1TSHRLMNAUSP2NPSR1 | |
| SCHEMBL10990432 | 0.83 | CYP3A4 (0.45) | ALDH1A1TSHRLMNAUSP2NPSR1 | |
| SCHEMBL10997843 | 0.83 | CYP3A4 (0.45) | ALDH1A1TSHRLMNAUSP2NPSR1 | |
| SCHEMBL10991908 | 0.83 | RAB9A (0.56) | MAPTALDH1A1LMNANPSR1KCNA5 | |
| SCHEMBL10996565 | 0.82 | TSHR (0.46) | MAPTALDH1A1TSHRLMNAUSP2 | |
| SCHEMBL10995044 | 0.81 | ALDH1A1 (0.48) | ATMALDH1A1LMNAKCNA5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |