Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CTSV | O60911 | 4/20 | 0.54 |
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988460 | 0.91 | MT-CO2 (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10833896 | 0.88 | CTSV (0.69) | MAPTMEN1KMT2ASIRT2ALDH1A1 | |
| SCHEMBL10937794 | 0.86 | SIRT2 (0.61) | MAPTMEN1KMT2ASIRT2ALDH1A1 | |
| SCHEMBL10985039 | 0.83 | MAPT (0.69) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10834468 | 0.83 | SIRT2 (0.57) | MAPTMEN1KMT2ASIRT2ALDH1A1 | |
| SCHEMBL11693283 | 0.80 | SIRT2 (0.54) | MAPTMEN1KMT2ASIRT2ALDH1A1 | |
| SCHEMBL11019583 | 0.79 | SMN1; SMN2 (0.57) | MAPTMEN1KMT2ASIRT2ALDH1A1 | |
| SCHEMBL10993168 | 0.79 | SMN1; SMN2 (0.55) | MAPTMEN1KMT2ASIRT2ALDH1A1 | |
| SCHEMBL28689403 | 0.78 | MT-CO2 (0.72) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8834618 | 0.77 | SIRT2 (0.63) | MAPTSIRT2ALDH1A1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | claimed |
| US-4549016-A | LIPOXYGENASE INHIBITORS, ANTIALLERGENS, ANTIASTHMA AGENTS | STERLING DRUG INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4510139-A | ANTYIALLERGENS; ASTHMA | STERLING DRUG INC. (US) | 1985-04-09 | — | — | US | disclosed |