Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019348 | 0.85 | SIRT2 (0.51) | SMN1; SMN2ALDH1A1MAPTALOX12GAA | |
| SCHEMBL11020058 | 0.84 | SIRT2 (0.61) | SMN1; SMN2ALDH1A1MAPTGAAEGFR | |
| SCHEMBL9702575 | 0.83 | TUBB4A (0.48) | MAPTGAANPC1RAB9ALMNA | |
| SCHEMBL10833896 | 0.81 | CTSV (0.69) | SMN1; SMN2ALDH1A1MAPTALOX12GAA | |
| SCHEMBL10937794 | 0.81 | SIRT2 (0.61) | SMN1; SMN2ALDH1A1MAPTALOX12GAA | |
| SCHEMBL866939 | 0.79 | NPC1 (0.60) | SMN1; SMN2ALDH1A1MAPTGAAEGFR | |
| SCHEMBL10995472 | 0.79 | MAPT (0.58) | SMN1; SMN2ALDH1A1MAPTALOX12GAA | |
| SCHEMBL9703808 | 0.78 | EGFR (0.59) | SMN1; SMN2ALDH1A1MAPTALOX12GAA | |
| SCHEMBL30211932 | 0.77 | MTNR1A (0.60) | MAOB | |
| SCHEMBL6034576 | 0.77 | MAOB (0.55) | SMN1; SMN2ALDH1A1MAPTALOX12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | claimed |
| EP-0122518-A1 | Phenylaminobenzenealkanols and preparation | STERLING DRUG INC. (US) | 1984-10-24 | — | — | EP | claimed |
| US-4496590-A | TREATMENT OR PREVENTION OF ALLERGIC ASTHMA, ANTI-ASTHMATIC | STERLING DRUG INC. (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0122518-A1 | Phenylaminobenzenealkanols and preparation | STERLING DRUG INC. (US) | 1984-10-24 | — | — | EP | disclosed |