Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845492 | 0.85 | — | — | |
| SCHEMBL9845446 | 0.81 | LMNA (0.36) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10910689 | 0.80 | HTR2A (0.37) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10910976 | 0.80 | MEN1 (0.39) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10997214 | 0.80 | L3MBTL1 (0.33) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10997207 | 0.78 | LMNA (0.37) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10995825 | 0.77 | KMT2A (0.36) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10911010 | 0.76 | RAB9A (0.36) | LMNAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9845439 | 0.74 | LMNA (0.31) | LMNAMEN1KMT2ASMN1; SMN2CES1 | |
| SCHEMBL10909271 | 0.72 | CES1 (0.50) | LMNAMEN1KMT2ACES1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537888-A | Substituted benzoxazine derivatives and fungicidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-27 | — | — | US | disclosed |
| EP-0103797-A2 | Substituted benzoxazine derivatives | BAYER AG (DE) | 1984-03-28 | — | — | EP | disclosed |