Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910689 | 0.84 | HTR2A (0.37) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL10910976 | 0.84 | MEN1 (0.39) | LMNAL3MBTL1HSD17B10MEN1KMT2A | |
| SCHEMBL10997214 | 0.84 | L3MBTL1 (0.33) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL10997207 | 0.81 | LMNA (0.37) | LMNAL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10995658 | 0.81 | LMNA (0.32) | LMNAL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10995825 | 0.80 | KMT2A (0.36) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL10911010 | 0.79 | RAB9A (0.36) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL9845492 | 0.78 | — | — | |
| SCHEMBL9845439 | 0.77 | LMNA (0.31) | LMNAMEN1KMT2ASMN1; SMN2CES1 | |
| SCHEMBL9845452 | 0.77 | MEN1 (0.38) | LMNAL3MBTL1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406993-A2 | Substituted benzoxazolinone and benzoxazinone derivatives, process for their preparation and their use as agent with herbicide activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |