Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996371 | 1.00 | GAA (0.43) | GAALMNAALDH1A1HPGDMAPT | |
| SCHEMBL574219 | 0.90 | HPGD (0.45) | GAAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL574218 | 0.90 | HPGD (0.45) | GAAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL11197357 | 0.85 | KDM4E (0.37) | GAALMNAALDH1A1HPGDMAPT | |
| SCHEMBL21436402 | 0.85 | KDM4E (0.37) | GAALMNAALDH1A1HPGDMAPT | |
| SCHEMBL11000446 | 0.84 | VCAM1 (0.44) | GAALMNAALDH1A1HPGDMAPT | |
| SCHEMBL11000444 | 0.84 | VCAM1 (0.44) | GAALMNAALDH1A1HPGDMAPT | |
| SCHEMBL11004620 | 0.83 | GAA (0.41) | GAALMNAALDH1A1HPGDMAPT | |
| SCHEMBL10998937 | 0.83 | GAA (0.41) | GAALMNAALDH1A1HPGDMAPT | |
| SCHEMBL11512796 | 0.82 | ALDH1A1 (0.49) | GAALMNAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492710-A | Substituted pyrrolidinyl-benzoic acid derivatives and a process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | disclosed |