Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | USP10 | Q14694 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000444 | 1.00 | VCAM1 (0.44) | VCAM1LMNAGAAMEN1KMT2A | |
| SCHEMBL573280 | 0.91 | VCAM1 (0.45) | VCAM1LMNAGAAMEN1KMT2A | |
| SCHEMBL573281 | 0.91 | VCAM1 (0.45) | VCAM1LMNAGAAMEN1KMT2A | |
| SCHEMBL21436487 | 0.87 | VCAM1 (0.43) | VCAM1MEN1KMT2AERN1MAPT | |
| SCHEMBL21436486 | 0.87 | VCAM1 (0.43) | VCAM1MEN1KMT2AERN1MAPT | |
| SCHEMBL11510885 | 0.85 | MAPT (0.43) | VCAM1LMNAGAAMEN1KMT2A | |
| SCHEMBL11511421 | 0.84 | ALDH1A1 (0.43) | VCAM1LMNAGAAMEN1KMT2A | |
| SCHEMBL10996368 | 0.84 | GAA (0.43) | LMNAGAAKMT2AMAPTCYP2C9 | |
| SCHEMBL10996371 | 0.84 | GAA (0.43) | LMNAGAAKMT2AMAPTCYP2C9 | |
| SCHEMBL573292 | 0.82 | VCAM1 (0.47) | VCAM1LMNAMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492710-A | Substituted pyrrolidinyl-benzoic acid derivatives and a process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | disclosed |