SCHEMBL1099677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1099983	0.85	TRPM8 (0.49)	TRPM8HIF1A
	SCHEMBL1097915	0.85	TRPM8 (0.58)	TRPM8MEN1KMT2ALMNASMN1; SMN2
	SCHEMBL1098317	0.84	TRPM8 (0.60)	TRPM8
	SCHEMBL1098004	0.84	TRPM8 (0.54)	TRPM8
	SCHEMBL1098802	0.83	TRPM8 (0.56)	TRPM8LMNA
	SCHEMBL1098468	0.80	ROCK2 (0.39)	TRPM8ROCK2ROCK1P2RX7MEN1
	SCHEMBL1098782	0.79	TRPM8 (0.68)	TRPM8MEN1KMT2A
	SCHEMBL1097655	0.78	TRPM8 (0.55)	TRPM8MEN1KMT2ALMNA
	SCHEMBL1098244	0.78	TRPM8 (0.59)	TRPM8MEN1KMT2A
	SCHEMBL1098363	0.78	TRPM8 (0.55)	TRPM8HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.