Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635208 | 0.79 | MAPT (0.50) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL7386575 | 0.79 | RAB9A (0.57) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL2048120 | 0.78 | LMNA (0.58) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL26097662 | 0.78 | LMNA (0.58) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL3820072 | 0.78 | LMNA (0.58) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL12005279 | 0.78 | MAPT (0.42) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL8773277 | 0.78 | MAPT (0.50) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL15104997 | 0.76 | MAPT (0.47) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL5847033 | 0.74 | ABCB1 (0.48) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL5393003 | 0.73 | PPARG (0.49) | MAPTKDM4EALOX15HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525426-A | WITH IMPROVED THERMOFORMABILITY RESISTANCE TO ABRASION AND ENVIRONMENTAL DEGRADATION | GENERAL ELECTRIC COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| US-4495360-A | SILICONE PROTECTIVE COATINGS; METHOXY- SUBSTITUTED SILYL BENZOPHENONES; DURABILITY | GENERAL ELECTRIC COMPANY (US) | 1985-01-22 | — | — | US | disclosed |