Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799654 | 0.90 | DRD2 (0.51) | MAPTDRD2DRD1DRD3RAB9A | |
| SCHEMBL8773277 | 0.88 | MAPT (0.50) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL4635208 | 0.82 | MAPT (0.50) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL7386575 | 0.82 | RAB9A (0.57) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL3820072 | 0.81 | LMNA (0.58) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL26097662 | 0.81 | LMNA (0.58) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL2048120 | 0.81 | LMNA (0.58) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL6245392 | 0.81 | ABCB1 (0.49) | MAPTDRD2DRD1DRD3RAB9A | |
| SCHEMBL15104997 | 0.79 | MAPT (0.47) | MAPTKDM4EALOX15HSD17B10MAPK1 | |
| SCHEMBL10996803 | 0.78 | MAPT (0.42) | MAPTKDM4EALOX15HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940397-B2 | Weatherable and abrasion resistant coating systems for polymeric substrates | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-01-27 | — | — | US | disclosed |
| US-20120219803-A1 | Weatherable & Abrasion Resistant Coating Systems for Polymeric Substrates | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-08-30 | — | — | US | disclosed |