Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246807 | 0.90 | DRD2 (0.53) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL12005279 | 0.88 | MAPT (0.42) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL4635208 | 0.81 | MAPT (0.50) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL2048120 | 0.81 | LMNA (0.58) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL26097662 | 0.81 | LMNA (0.58) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL3820072 | 0.81 | LMNA (0.58) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL1696776 | 0.79 | MAPT (0.76) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7386575 | 0.78 | RAB9A (0.57) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL15104997 | 0.78 | MAPT (0.47) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL10996803 | 0.78 | MAPT (0.42) | MAPTKDM4EHSD17B10MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570165-B1 | Heat curable primerless silicone hardcoat compositions, and thermoplastic composites | GEN ELECTRIC (US) | 1997-10-29 | — | — | EP | disclosed |