Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.34 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657507 | 0.84 | MAPT (0.43) | ALDH1A1TP53NPC1GPX4RAB9A | |
| SCHEMBL10997528 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TP53NPC1GPX4RAB9A | |
| SCHEMBL9314947 | 0.80 | TP53 (0.49) | ALDH1A1TP53NPC1MAPTLMNA | |
| SCHEMBL8388252 | 0.79 | TP53 (0.48) | ALDH1A1TP53NPC1MAPTLMNA | |
| SCHEMBL15131654 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TP53NPC1GPX4RAB9A | |
| SCHEMBL14785503 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TP53NPC1GPX4RAB9A | |
| SCHEMBL11357273 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TP53NPC1GPX4RAB9A | |
| SCHEMBL10657503 | 0.74 | RECQL (0.39) | ALDH1A1TP53NPC1GPX4RAB9A | |
| SCHEMBL9114792 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TP53NPC1GPX4RAB9A | |
| SCHEMBL10663663 | 0.73 | RAB9A (0.50) | ALDH1A1TP53NPC1RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052578-B1 | MONOAZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1985-10-09 | — | — | EP | disclosed |
| US-4447358-A | FOR POLYAMIDE AND WOOL TEXTILE DYEING | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |