Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632720 | 0.83 | SRC (0.44) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10633051 | 0.80 | CHEK2 (0.41) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10520071 | 0.73 | MEN1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL874998 | 0.70 | KDM4E (0.56) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL10632495 | 0.68 | MAPT (0.61) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL874942 | 0.67 | TUBB4A (0.46) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL23327604 | 0.66 | MEN1 (0.39) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL31414248 | 0.63 | KDM4E (0.63) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| Formamide SCHEMBL28481009 | 0.63 | HPGD (0.46) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL10429367 | 0.63 | HPGD (0.47) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496725-A | Substituted 1,2,3-triazino[4',5':4,5]-thieno[2,3-B]quinolin-4(3H)-ones | THE DOW CHEMICAL COMPANY (US) | 1985-01-29 | — | — | US | disclosed |