Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511671 | 0.91 | VCAM1 (0.43) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL11000446 | 0.85 | VCAM1 (0.44) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL11000444 | 0.85 | VCAM1 (0.44) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL11004620 | 0.84 | GAA (0.41) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL11511421 | 0.82 | ALDH1A1 (0.43) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL573293 | 0.81 | VCAM1 (0.47) | MAPTLMNAALDH1A1POLBMAPK1 | |
| SCHEMBL573292 | 0.81 | VCAM1 (0.47) | MAPTLMNAALDH1A1POLBMAPK1 | |
| SCHEMBL21436415 | 0.80 | VCAM1 (0.41) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL21436513 | 0.80 | VCAM1 (0.41) | MAPTKMT2AALDH1A1GAAPOLB | |
| SCHEMBL21436994 | 0.80 | VCAM1 (0.41) | MAPTKMT2AALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172142-A | DIURETICS FOR TREATMENT OF EDEMA | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |