Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | F13A1 | P00488 | 3/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL3454140 | 0.98 | TSHR (0.55) | LMNANFKB1TSHRPMP22PTGS1 | |
| Sebacic Acid SCHEMBL8856373 | 0.98 | TSHR (0.55) | LMNANFKB1TSHRPMP22PTGS1 | |
| Adipic Acid SCHEMBL9696395 | 0.96 | LMNA (0.48) | LMNANFKB1TSHRPMP22PTGS1 | |
| Sebacic Acid SCHEMBL27554744 | 0.92 | GPR84 (0.52) | LMNANFKB1TSHRPMP22PTGS1 | |
| Succinic Acid SCHEMBL8472894 | 0.90 | LMNA (0.47) | LMNAPTGS1PTGS2F13A1SLC22A6 | |
| Dodecanoate SCHEMBL30877485 | 0.88 | GPR84 (0.63) | LMNATSHRSLC22A6GPR84FFAR1 | |
| Valeric Acid SCHEMBL5438662 | 0.87 | AKR1B1 (0.52) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| Maleic Anhydride SCHEMBL11253459 | 0.87 | PTGS1 (0.43) | LMNANFKB1TSHRPMP22PTGS1 | |
| Adipic Acid SCHEMBL735379 | 0.85 | PTGS1 (0.39) | LMNANFKB1TSHRPMP22PTGS1 | |
| Maleic Anhydride SCHEMBL1286835 | 0.84 | TSHR (0.44) | LMNANFKB1TSHRPMP22PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894854-A | Waterborne polyurethane surface layer resin and preparation method and application thereof | 旭川化学（苏州）有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115894854-A | Waterborne polyurethane surface layer resin and preparation method and application thereof | 旭川化学（苏州）有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-104837637-A | Fabric pretreatment for digital printing | LUBRIZOL ADVANCED MAT INC | 2015-08-12 | — | — | CN | disclosed |
| CN-101613457-B | Breathable polyurethanes, blends, and articles | LUBRIZOL ADVANCED MAT INC | 2012-10-17 | — | — | CN | disclosed |
| CN-102575051-A | Hydrolytically stable polyurethane nanocomposites | LUBRIZOL ADVANCED MAT INC | 2012-07-11 | — | — | CN | disclosed |
| US-4496675-A | Aqueous dispersions based on a polyurethane synthetic resin | BASF FARBEN & FASERN AG (DE) | 1985-01-29 | — | — | US | disclosed |