Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 3/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Anhydride SCHEMBL11253459 | 0.95 | PTGS1 (0.43) | TSHRSLC22A6PTGS1PTGS2LMNA | |
| Adipic Acid SCHEMBL11001007 | 0.84 | LMNA (0.52) | TSHRSLC22A6PTGS1PTGS2LMNA | |
| Sebacic Acid SCHEMBL3454140 | 0.82 | TSHR (0.55) | TSHRSLC22A6PTGS1PTGS2LMNA | |
| Sebacic Acid SCHEMBL8856373 | 0.82 | TSHR (0.55) | TSHRSLC22A6PTGS1PTGS2LMNA | |
| Adipic Acid SCHEMBL9696395 | 0.80 | LMNA (0.48) | TSHRSLC22A6PTGS1PTGS2LMNA | |
| Maleic Anhydride SCHEMBL27706599 | 0.80 | DGKA (0.44) | LMNAMAPK1 | |
| Succinic Acid SCHEMBL8472894 | 0.80 | LMNA (0.47) | SLC22A6PTGS1PTGS2MMP3LMNA | |
| SCHEMBL1289888 | 0.79 | SLC22A6 (0.65) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL19925 | 0.79 | SLC22A6 (0.65) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL10784802 | 0.78 | TSHR (0.44) | TSHRSLC22A6NPC1LMNAF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820844-B2 | Charge-modified particles and methods of making the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-11-21 | — | — | US | disclosed |
| EP-3768794-B1 | CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3768794-A2 | CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME | 3M Innovative Properties Company (US) | 2021-01-27 | — | — | EP | disclosed |
| EP-3768655-A1 | MODIFIED ALUMINUM NITRIDE PARTICLES AND METHODS OF MAKING THE SAME | 3M Innovative Properties Company (US) | 2021-01-27 | — | — | EP | disclosed |
| US-10894903-B2 | Nanoparticle filled barrier adhesive compositions | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-01-19 | — | — | US | disclosed |
| US-20210009811-A1 | MODIFIED ALUMINUM NITRIDE PARTICLES AND METHODS OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2021-01-14 | — | — | US | disclosed |
| US-20210002137-A1 | CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2021-01-07 | — | — | US | disclosed |
| EP-2620413-B1 | Continuous hydrothermal reactor system comprising a fluorinated polymer tubular reactor | 3M INNOVATIVE PROPERTIES CO (US) | 2020-07-01 | — | — | EP | disclosed |
| EP-2507320-B1 | METHOD OF INHIBITING WATER ADSORPTION OF POWDER BY ADDITION OF HYDROPHOBIC NANOPARTICLES | 3M INNOVATIVE PROPERTIES CO (US) | 2020-05-27 | — | — | EP | disclosed |
| WO-2019180619-A1 | MODIFIED ALUMINUM NITRIDE PARTICLES AND METHODS OF MAKING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-09-26 | — | — | WO | disclosed |
| US-20120233929-A1 | METHOD OF INHIBITING WATER ADSORPTION OF POWDER BY ADDITION OF HYDROPHOBIC NANAOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY | 2012-09-20 | — | — | US | disclosed |
| US-20120100373-A1 | METHOD OF MILLING PARTICLES WITH NANOPARTICLES AND MILLED FREE-FLOWING POWDER | 3M INNOVATIVE PROPERTIES COMPANY | 2012-04-26 | — | — | US | disclosed |
| WO-2012047691-A2 | METHOD OF MODIFYING DISSOLUTION RATE OF PARTICLES BY ADDITION OF HYDROPHOBIC NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2011068742-A1 | METHOD OF INHIBITING WATER ADSORPTION OF POWDER BY ADDITION OF HYDROPHOBIC NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011068678-A1 | METHOD OF ELECTROSTATIC DEPOSITION OF PARTICLES, ABRASIVE GRAIN AND ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011063222-A2 | INORGANIC PIGMENT COMPOSITIONS COMPRISING SURFACE-MODIFIED NANOPARTICLES, AND METHODS OF MAKING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-05-26 | — | — | WO | disclosed |
| WO-2010151435-A1 | METHOD OF MILLING PARTICLES WITH NANOPARTICLES AND MILLED FREE-FLOWING POWDER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-12-29 | — | — | WO | disclosed |
| US-20100276374-A1 | METHOD OF MAKING ZIRCONIA-CONTAINING NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY | 2010-11-04 | — | — | US | disclosed |
| EP-2244982-A2 | METHOD OF MAKING ZIRCONIA-CONTAINING NANOPARTICLES | 3M Innovative Properties Company (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009085926-A2 | METHOD OF MAKING ZIRCONIA-CONTAINING NANOPARTICLES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002137-A1 | CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME | PCTP, MBOAT1, CA13 | TSHR 1659/4885SLC22A6 1665/4885NPC1 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.